APP G2019s
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- Submitted
- Validated
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Position #5 of 7 queued folds
Estimated wait: ~5 days (based on ~1 fold per day capacity)
Rationale
The LRRK2 G2019S mutation is the most common genetic determinant of Parkinson's disease (PD) identified to date. This mutation, reported in both familial and sporadic PD, occurs at elevated frequencies in Maghreb population. In the present study, we examined the prevalence of the G2019S mutation in the Moroccan population and we compared the motor and nonmotor phenotype of G2019S carriers to patients with idiopathic Parkinson's disease.
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Activity Log
Hypothesis submitted
Validation Results
UniProt
Found
Gene: APP
Protein: Amyloid-beta precursor protein
Accession: P05067
ClinVar
Not Found
No clinical annotations found for this variant
gnomAD
Not Found
No population frequency data found
PubMed
7 papers found
7 publications mention this protein variant